Negative reaction data for adjuvant treatment are based upon the ATAC trial [seeClinical Studies (14.1)] The median period of adjuvant therapy for safety and security examination was 59.8 months and 59.6 months for people getting Arimidex 1 mg and also tamoxifen 20 mg, respectively.

The price of long term (even more compared to 24 weeks) secure disease, the price of development, and survival were also computed.

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It is not recognized whether these impacts observed in women rats are a sign of impaired fertility in people.